Cadherin 13 antibody (AA 475-525)

Catalog No. ABIN7451103

This anti-Cadherin 13 antibody is a Rabbit Polyclonal antibody detecting Cadherin 13 in IP. Suitable for Human.

Quick Overview for Cadherin 13 antibody (AA 475-525) (ABIN7451103)

Target: Cadherin 13 (CDH13)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cadherin 13 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-Cadherin 13 Antibody

Binding Specificity: AA 475-525

Purpose: Rabbit anti-Cadherin 13/CDH13/T-cadherin Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 475 and 525

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. ABIN7451103 has not performed satisfactorily when used for WB of Cadherin 13/CDH13/T-cadherin in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of Cadherin 13/CD.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Cadherin 13

Target: Cadherin 13 (CDH13)

Alternative Name: Cadherin 13/CDH13/T-cadherin

Background: Background: Cadherin-13 is a member of the cadherin superfamily. Cadherin-13 is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. Cadherin-13 lacks the cytoplasmic domain characteristic of other cadherins, and so is not thought to be a cell-cell adhesion glycoprotein. Cadherin-13 acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis [taken from NCBI Entrez Gene (Gene ID: 1012)].

Gene ID: 1012

UniProt: P55290

Pathways: EGFR Signaling Pathway, Cell-Cell Junction Organization