TADA3L antibody (AA 325-375)

Catalog No. ABIN7451125

This Rabbit Polyclonal antibody specifically detects TADA3L in IP. It exhibits reactivity toward Human.

Quick Overview for TADA3L antibody (AA 325-375) (ABIN7451125)

Target: TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TADA3L antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-TADA3L Antibody

Binding Specificity: AA 325-375

Purpose: Rabbit anti-TADA3/TADA3L Antibody, Affinity Purified

Predicted Reactivity: Mouse,Rat,X. laevis,X. tropicalis,Bovine,Orangutan

Purification: Affinity Purified

Immunogen: Between AA 325 and 375

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. ABIN7451125 has not performed satisfactorily when used for WB of TADA3/TADA3L in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of TADA3/TADA3L.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for TADA3L

Target: TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))

Alternative Name: TADA3/TADA3L

Background: Background: The gene TADA3, also known as ADA3 or TADA3L, encodes for the protein transcriptional adapter 3. TADA3/TADA3L is a transcriptional activator adaptor and a component of the histone acetyl transferase (HAT) coactivator complex which plays a crucial role in chromatin modulation and cell cycle progression. Transcriptional adapter 3 is also involved in the stabilization and activation of the p53 tumor suppressor protein that plays a role in the cellular response to DNA damage [taken from NCBI Entrez Gene (Gene ID: 10474)].

Gene ID: 10474

UniProt: O75528

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway