Lipin 1 antibody (AA 225-275)

Catalog No. ABIN7451137

This Rabbit Polyclonal antibody specifically detects Lipin 1 in IP. It exhibits reactivity toward Human.

Quick Overview for Lipin 1 antibody (AA 225-275) (ABIN7451137)

Target: Lipin 1 (LPIN1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lipin 1 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-Lipin 1 Antibody

Binding Specificity: AA 225-275

Purpose: Rabbit anti-LPIN1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 225 and 275

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. ABIN7451137 has not performed satisfactorily when used for WB of LPIN1 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of LPIN1.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Lipin 1

Target: Lipin 1 (LPIN1)

Alternative Name: LPIN1

Background: Background: LPIN1 is a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. LPIN1 is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolis [taken from NCBI Entrez Gene (Gene ID: 23175)].

Gene ID: 23175

UniProt: Q14693

Pathways: Monocarboxylic Acid Catabolic Process