MSH3 antibody (AA 1025-1075)

Catalog No. ABIN7451138

The Rabbit Polyclonal anti-MSH3 antibody has been validated for IP. It is suitable to detect MSH3 in samples from Human.

Quick Overview for MSH3 antibody (AA 1025-1075) (ABIN7451138)

Target: MSH3 (MutS Homolog 3 (MSH3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MSH3 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-MSH3 Antibody

Binding Specificity: AA 1025-1075

Purpose: Rabbit anti-MSH3 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 1025 and 1075

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. ABIN7451138 has not performed satisfactorily when used for WB of MSH3 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of MSH3.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for MSH3

Target: MSH3 (MutS Homolog 3 (MSH3))

Alternative Name: MSH3

Background: Background: MSH3 forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer [taken from NCBI Entrez Gene (Gene ID: 4437)].

Gene ID: 4437

UniProt: P20585

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response