FDFT1 antibody (AA 100-150)

Catalog No. ABIN7451159

The Rabbit Polyclonal anti-FDFT1 antibody has been validated for IP. It is suitable to detect FDFT1 in samples from Human.

Quick Overview for FDFT1 antibody (AA 100-150) (ABIN7451159)

Target: FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FDFT1 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-FDFT1 Antibody

Binding Specificity: AA 100-150

Purpose: Rabbit anti-FDFT1 Antibody, Affinity Purified

Predicted Reactivity: Mouse,Bovine,Orangutan

Purification: Affinity Purified

Immunogen: Between AA 100 and 150

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. ABIN7451159 has not performed satisfactorily when used for WB of FDFT1 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of FDFT1.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for FDFT1

Target: FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))

Alternative Name: FDFT1

Background: Background: Farnesyl-diphosphate farnesyltransferase 1 (FDFT1) is a membrane-associated enzyme located at a branch point in the mevalonate pathway. FDFT1 is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene [taken from NCBI Entrez Gene (Gene ID: 2222)].

Gene ID: 2222

UniProt: P37268

Pathways: Regulation of Lipid Metabolism by PPARalpha