MPI antibody (AA 25-75)
Quick Overview for MPI antibody (AA 25-75) (ABIN7451179)
Target
See all MPI AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 25-75
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Purpose
- Rabbit anti-MPI Antibody, Affinity Purified
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Predicted Reactivity
- Chimpanzee
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Purification
- Affinity Purified
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Immunogen
- Between AA 25 and 75
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Isotype
- IgG
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Application Notes
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IP: 2 - 10 μg/mg lysate
WB: Not recommended. ABIN7451179 has not performed satisfactorily when used for WB of MPI in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of MPI.
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- MPI (Mannose Phosphate Isomerase (MPI))
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Alternative Name
- MPI
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Background
- Background: Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib. Alternative splicing results in multiple transcript variants [taken from NCBI Entrez Gene (Gene ID: 4351)].
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Gene ID
- 4351
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UniProt
- P34949
Target
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