GMDS antibody (AA 322-372)

Catalog No. ABIN7451184

This anti-GMDS antibody is a Rabbit Polyclonal antibody detecting GMDS in IP. Suitable for Human.

Quick Overview for GMDS antibody (AA 322-372) (ABIN7451184)

Target: GMDS (GDP-Mannose 4,6-Dehydratase (GMDS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GMDS antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-GMDS Antibody

Binding Specificity: AA 322-372

Purpose: Rabbit anti-GMDS Antibody, Affinity Purified

Predicted Reactivity: Mouse

Purification: Affinity Purified

Immunogen: Between AA 322 and 372

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. ABIN7451184 has not performed satisfactorily when used for WB of GMDS in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of GMDS.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for GMDS

Target: GMDS (GDP-Mannose 4,6-Dehydratase (GMDS))

Alternative Name: GMDS

Background: Background: GDP-mannose 4,6-dehydratase (GMDS) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020) [taken from NCBI Entrez Gene (Gene ID: 2762)].

Gene ID: 2762

UniProt: O60547