ANAPC10 antibody (AA 135-185)

Catalog No. ABIN7451192

The Rabbit Polyclonal anti-ANAPC10 antibody has been validated for IP. It is suitable to detect ANAPC10 in samples from Human.

Quick Overview for ANAPC10 antibody (AA 135-185) (ABIN7451192)

Target: ANAPC10 (Anaphase Promoting Complex Subunit 10 (ANAPC10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANAPC10 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-ANAPC10 Antibody

Binding Specificity: AA 135-185

Purpose: Rabbit anti-ANAPC10/APC10 Antibody, Affinity Purified

Predicted Reactivity: Mouse,Bovine

Purification: Affinity Purified

Immunogen: Between AA 135 and 185

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-ANAPC10/APC10 antibody ABIN7450972.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for ANAPC10

Target: ANAPC10 (Anaphase Promoting Complex Subunit 10 (ANAPC10))

Alternative Name: ANAPC10/APC10

Background: Background: ANAPC10/APC10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1, MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1, MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1, MIM 116940) (summary by Wendt et al., 2001 [PubMed 11524682]) [taken from NCBI Entrez Gene (Gene ID: 10393)].

Gene ID: 10393

UniProt: Q9UM13

Pathways: M Phase