DOCK2 antibody (AA 550-600)
Quick Overview for DOCK2 antibody (AA 550-600) (ABIN7451231)
Target
See all DOCK2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 550-600
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Purpose
- Rabbit anti-DOCK2 Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogen
- Between AA 550 and 600
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Isotype
- IgG
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Application Notes
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IP: 2 - 10 μg/mg lysate
WB: Not recommended. Use rabbit anti-DOCK2 antibody ABIN7450182.
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- DOCK2 (Dedicator of Cytokinesis 2 (DOCK2))
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Alternative Name
- DOCK2
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Background
- Background: Dedicator of cytokinesis protein 2 (DOCK2) is Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. DOCK2 activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. DOCK2 may also participate in IL2 transcriptional activation via the activation of RAC2 [taken from the Universal Protein Resource (UniProt) Q92608].
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Gene ID
- 1794
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UniProt
- Q92608
Target
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