RALBP1 antibody (AA 600-650)

Catalog No. ABIN7451325

This anti-RALBP1 antibody is a Rabbit Polyclonal antibody detecting RALBP1 in IP. Suitable for Human.

Quick Overview for RALBP1 antibody (AA 600-650) (ABIN7451325)

Target: RALBP1 (RalA Binding Protein 1 (RALBP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RALBP1 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-RALBP1 Antibody

Binding Specificity: AA 600-650

Purpose: Rabbit anti-RLIP76 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 600 and 650

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-RLIP76 antibody ABIN7450662.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for RALBP1

Target: RALBP1 (RalA Binding Protein 1 (RALBP1))

Alternative Name: RLIP76

Background: Background: 76 kDa Ral-interacting protein (RLIP76) can activate, specifically, hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. RLIP76 mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. It can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. It serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin [taken from the Universal Protein Resource (UniProt) Q15311].

Gene ID: 10928

NCBI Accession: NP_006779

UniProt: Q15311