LDLR antibody (AA 810-860)

Catalog No. ABIN7451468

The Rabbit Polyclonal anti-LDLR antibody has been validated for IP. It is suitable to detect LDLR in samples from Human.

Quick Overview for LDLR antibody (AA 810-860) (ABIN7451468)

Target: LDLR (Low Density Lipoprotein Receptor (LDLR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LDLR antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-LDLR Antibody

Binding Specificity: AA 810-860

Purpose: Rabbit anti-LDLR Antibody, Affinity Purified

Predicted Reactivity: Mouse,Rat,Bovine,Rabbit

Purification: Affinity Purified

Immunogen: Between AA 810 and 860

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for LDLR

Target: LDLR (Low Density Lipoprotein Receptor (LDLR))

Alternative Name: LDLR

Background: Background: Low-density lipoprotein receptor, LDLR, binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, LDLR functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cell [taken from NCBI Entrez Gene (Gene ID: 3949)].

Gene ID: 3949

NCBI Accession: NP_000518

UniProt: P01130

Pathways: Hepatitis C, Lipid Metabolism