POLR3E antibody (AA 175-225)

Catalog No. ABIN7451494

This Rabbit Polyclonal antibody specifically detects POLR3E in IP. It exhibits reactivity toward Human.

Quick Overview for POLR3E antibody (AA 175-225) (ABIN7451494)

Target: POLR3E (Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLR3E antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-POLR3E Antibody

Binding Specificity: AA 175-225

Purpose: Rabbit anti-POLR3E Antibody, Affinity Purified

Predicted Reactivity: Mouse

Purification: Affinity Purified

Immunogen: Between AA 175 and 225

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for POLR3E

Target: POLR3E (Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E))

Alternative Name: POLR3E

Background: Background: POLR3E (RNA polymerase III polypeptide E 80 kDa) is a DNA-dependent RNA polymerase that catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. POLR3E is a specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. It is essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters. POLR3E plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses [taken from the Universal Protein Resource (UniProt) Q9NVU0].

Gene ID: 55718

NCBI Accession: NP_060589

UniProt: Q9NVU0