SORD antibody (AA 1-50)

Catalog No. ABIN7451514

This anti-SORD antibody is a Rabbit Polyclonal antibody detecting SORD in IP. Suitable for Human.

Quick Overview for SORD antibody (AA 1-50) (ABIN7451514)

Target: SORD (Sorbitol Dehydrogenase (SORD))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SORD antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-SORD Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-SORD Antibody, Affinity Purified

Predicted Reactivity: Sheep,Bovine,Pig,Orangutan

Purification: Affinity Purified

Immunogen: between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SORD

Target: SORD (Sorbitol Dehydrogenase (SORD))

Alternative Name: SORD

Background: Background: Sorbitol dehydrogenase (SORD) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase, makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor [taken from NCBI Entrez Gene (Gene ID: 6652)].

Gene ID: 6652

NCBI Accession: NP_003095

UniProt: Q00796