FNBP1L antibody (AA 50-100)
Quick Overview for FNBP1L antibody (AA 50-100) (ABIN7451530)
Target
See all FNBP1L AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 50-100
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Purpose
- Rabbit anti-Toca-1 Antibody, Affinity Purified
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Predicted Reactivity
- Mouse,Rat
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Purification
- Affinity Purified
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Immunogen
- between AA 50 and 100
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Isotype
- IgG
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Application Notes
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IP: 2 - 10 μg/mg lysate
WB: Not recommended
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- FNBP1L (Formin Binding Protein 1-Like (FNBP1L))
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Alternative Name
- Toca-1
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Background
- Background: Toca-1 is required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Toca-1 may bind to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promote membrane invagination and the formation of tubules. Toca-1 also promotes CDC42-induced actin polymerization by activating the WASL/N-WASP-WASPIP/WIP complex, the predominant form of WASL/N-WASP in cells [taken from the Universal Protein Resource (UniProt) Q5T0N5].
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Gene ID
- 54874
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NCBI Accession
- NP_001157945
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UniProt
- Q5T0N5
Target
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