INTS1 antibody (AA 150-200)

Catalog No. ABIN7451568

This anti-INTS1 antibody is a Rabbit Polyclonal antibody detecting INTS1 in WB and IP. Suitable for Human and Mouse.

Quick Overview for INTS1 antibody (AA 150-200) (ABIN7451568)

Target: INTS1 (Integrator Complex Subunit 1 (INTS1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INTS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-INTS1 Antibody

Binding Specificity: AA 150-200

Purpose: Rabbit anti-INT1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 150 and 200

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:1,000 - 1:2,500

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for INTS1

Target: INTS1 (Integrator Complex Subunit 1 (INTS1))

Alternative Name: INT1

Background: Background: INT1 was first identified as KIAA1440, a hypothetical protein predicted from the in silico analysis of long cDNAs isolated in the Kazusa cDNA sequencing project. Targeted disruption of INT1 results in growth arrest at the early blastocyst stage, activated caspase-3/7 that results in apoptosis, and impaired processing of U2 snRNA. INT1 has been demonstrated to be the largest subunit of the integrator complex which functions to mediate U1 and U2 snRNA 3'end processing.

Gene ID: 26173

NCBI Accession: XP_291222

UniProt: Q8N201