Ataxin 10 antibody (AA 425-475)

Catalog No. ABIN7451653

This Rabbit Polyclonal antibody specifically detects Ataxin 10 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for Ataxin 10 antibody (AA 425-475) (ABIN7451653)

Target: Ataxin 10 (ATXN10)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ataxin 10 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-Ataxin 10 Antibody

Binding Specificity: AA 425-475

Purpose: Rabbit anti-ATXN10/SCA10 Antibody, Affinity Purified

Predicted Reactivity: Orangutan

Purification: Affinity Purified

Immunogen: between AA 425 and 475

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Ataxin 10

Target: Ataxin 10 (ATXN10)

Alternative Name: ATXN10/SCA10

Background: Background: Pentanucleotide repeat expansions in the ATXN10/SCA10 gene have been linked to spinocerebellar ataxia type 10, a disorder that is characterized by gait ataxia, cognitive development, and seizures. ATXN10/SCA10 is an evolutionarily conserved protein whose function has not been identified. It is proposed that the repeats in ATXN10/SCA10 may form unusual RNA hairpin structures that result in toxic RNA that may have biological effects such as sequestering of proteins, activation of enzymes, and deregulation of gene expression via the RNA interference pathway.

Gene ID: 25814

NCBI Accession: NP_037368

UniProt: Q9UBB4