CK1 epsilon antibody (AA 366-416)

Catalog No. ABIN7451709

This anti-CK1 epsilon antibody is a Rabbit Polyclonal antibody detecting CK1 epsilon in WB and IP. Suitable for Human.

Quick Overview for CK1 epsilon antibody (AA 366-416) (ABIN7451709)

Target: CK1 epsilon (CSNK1E) (Casein Kinase 1, epsilon (CSNK1E))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CK1 epsilon antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-CK1 epsilon Antibody

Binding Specificity: AA 366-416

Purpose: Rabbit anti-CKI epsilon Antibody, Affinity Purified

Predicted Reactivity: Mouse,Chicken

Purification: Affinity Purified

Immunogen: between AA 366 and 416

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CK1 epsilon

Target: CK1 epsilon (CSNK1E) (Casein Kinase 1, epsilon (CSNK1E))

Alternative Name: CKI epsilon

Background: Background: CKI epsilon is a member of the casein kinase 1 (CK1) serine/threonine kinase family of proteins. In mammals, there are seven distinct genes that represent the CK1 family: alpha, beta, gamma-1, gamma-2, gamma-3, delta, and epsilon. CKI epsilon phosphorylates a large number of proteins and is involved in pathways involving Wnt and AKT. CKI epsilon has been found to bind and phosphorylate the circadian protein, Period, and the Wnt signaling protein, Dsh. In the Wnt pathway, CKI epsilon activity is required for the full activation of Dsh and downstream signaling effects.

Gene ID: 1454

NCBI Accession: NP_001885

UniProt: P49674

Pathways: Hedgehog Signaling, M Phase