DAB2IP antibody (AA 850-900)

Catalog No. ABIN7451726

The Rabbit Polyclonal anti-DAB2IP antibody has been validated for WB and IP. It is suitable to detect DAB2IP in samples from Human and Mouse.

Quick Overview for DAB2IP antibody (AA 850-900) (ABIN7451726)

Target: DAB2IP (DAB2 Interacting Protein (DAB2IP))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAB2IP antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-DAB2IP Antibody

Binding Specificity: AA 850-900

Purpose: Rabbit anti-DAB2IP Antibody, Affinity Purified

Predicted Reactivity: Rat

Purification: Affinity Purified

Immunogen: between AA 850 and 900

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for DAB2IP

Target: DAB2IP (DAB2 Interacting Protein (DAB2IP))

Alternative Name: DAB2IP

Background: Background: DAB2-interacting protein (DAB2IP) functions as a Ras GTPase-activating protein. Through its interaction with MAP3K5, it disrupts the association of MAP3K5 with the inhibitory 14-3-3 complex. DAB2IP also Mediates TNF/TRAF2-induced MAP3K5-JNK activation, while it inhibits CHUK-NF-kappa-B signaling. DAB2IP may act as a tumor suppressor gene [taken from the Universal Protein Resource (UniProt) Q5VWQ8].

Gene ID: 153090

UniProt: Q5VWQ8

Pathways: EGFR Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Tube Formation