PAGR1 antibody (AA 1-50)

Catalog No. ABIN7451928

This anti-PAGR1 antibody is a Rabbit Polyclonal antibody detecting PAGR1 in WB and IP. Suitable for Human.

Quick Overview for PAGR1 antibody (AA 1-50) (ABIN7451928)

Target: PAGR1 (PAXIP1 Associated Glutamate-Rich Protein 1 (PAGR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAGR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-PAGR1 Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-PA1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PAGR1

Target: PAGR1 (PAXIP1 Associated Glutamate-Rich Protein 1 (PAGR1))

Alternative Name: PA1

Background: Background: PA1 (PTIP-associated protein 1) was isolated as a protein that associates with PTIP (Pax transactivation domain-interacting protein), a nuclear protein involved in the DNA damage response and interacts with the Pax2 transactivation domain. Along with PTIP, PA1 has been found to be present in a MLL3- and MLL4-containing Histone H3 Lysine 4 Methyltransferase complex. PA1 also appears to be important to the DNA damage response and repair. This involvement in DNA damage signaling is reported to be independent of its MLL association. PA1 has also been identified as GAS (glutamate-rich coactivator interacting with SRC1/NCOA1). As an interactor of SRC1 (steroid receptor coactivator 1), PA1 functions as a transcription cofactor.

Gene ID: 79447

NCBI Accession: NP_078792

UniProt: Q9BTK6