PKD2 antibody (AA 918-968)

Catalog No. ABIN7451972

The Rabbit Polyclonal anti-PKD2 antibody has been validated for WB and IP. It is suitable to detect PKD2 in samples from Human and Mouse.

Quick Overview for PKD2 antibody (AA 918-968) (ABIN7451972)

Target: PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PKD2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-PKD2 Antibody

Binding Specificity: AA 918-968

Purpose: Rabbit anti-Polycystin-2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 918 and 968

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PKD2

Target: PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

Alternative Name: Polycystin-2

Background: Background: Polycystin-2 is a calcium permeable cation channel. Defects in the Polycystin-2 gene, PKD2, are the cause of polycystic kidney disease autosomal dominant type 2 (ADPKD2) which is characterized by progressive formation and enlargement of cysts in both kidneys, typically leading to end-stage renal disease in adult life. Cysts also occur in the liver and other organs [taken from the Universal Protein Resource (UniProt) Q13563].

Gene ID: 5311

NCBI Accession: NP_000288

UniProt: Q13563

Pathways: cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity