PPP2R3B antibody (AA 350-400)

Catalog No. ABIN7451975

The Rabbit Polyclonal anti-PPP2R3B antibody has been validated for WB and IP. It is suitable to detect PPP2R3B in samples from Human.

Quick Overview for PPP2R3B antibody (AA 350-400) (ABIN7451975)

Target: PPP2R3B (Protein Phosphatase 2A 48 KDa Regulatory Subunit (PPP2R3B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2R3B antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-PPP2R3B Antibody

Binding Specificity: AA 350-400

Purpose: Rabbit anti-PPP2R3B Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 350 and 400

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PPP2R3B

Target: PPP2R3B (Protein Phosphatase 2A 48 KDa Regulatory Subunit (PPP2R3B))

Alternative Name: PPP2R3B

Background: Background: PP2A is a major serine/threonine phosphatase that is implicated in the negative control of cell cycle progression. It is a trimeric holoenzyme that is comprised of a catalytic, structural, and regulatory subunit. PPP2R3B is a regulatory subunit of PP2A. The regulatory subunits of PP2A are grouped into 3 families: B/PR55, B'/PR61, and B''/PR72. PPP2R3B encodes a 48 kDa B'' regulatory subunit. PPP2R3B and PP2A, in association with Cdc6, are implicated in cell cycle control via phosphatase activity targeted at DNA replication machinery. serine/threonine-protein phosphatase 2A 48 kDa regulatory subunit B, PP2A subunit B PR48 isoform, PPP2R3L, PR48, NY-REN-8, PPP2R3LY.

Gene ID: 28227

NCBI Accession: NP_037371

UniProt: Q9Y5P8

Pathways: PI3K-Akt Signaling, Mitotic G1-G1/S Phases