RPRD1B antibody (AA 276-326)

Catalog No. ABIN7452017

The Rabbit Polyclonal anti-RPRD1B antibody is suitable to detect RPRD1B in samples from Human and Mouse. It has been validated for WB and IP.

Quick Overview for RPRD1B antibody (AA 276-326) (ABIN7452017)

Target: RPRD1B (Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPRD1B antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-RPRD1B Antibody

Binding Specificity: AA 276-326

Purpose: Rabbit anti-RPRD1B Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 276 and 326

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for RPRD1B

Target: RPRD1B (Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B))

Alternative Name: RPRD1B

Background: Background: RPRD1B (regulation of nuclear pre-mRNA domain containing 1B) Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. RPRD1B is a transcriptional regulator that promotes cell proliferation and enhances the transcription of a number of cell cycle-related genes including CCND1, CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A [taken from the Universal Protein Resource (UniProt) Q9NQG5].

Gene ID: 58490

NCBI Accession: NP_067038

UniProt: Q9NQG5