SENP1 antibody (AA 1-50)

Catalog No. ABIN7452035

The Rabbit Polyclonal anti-SENP1 antibody has been validated for WB and IP. It is suitable to detect SENP1 in samples from Human.

Quick Overview for SENP1 antibody (AA 1-50) (ABIN7452035)

Target: SENP1 (SUMO1/sentrin Specific Peptidase 1 (SENP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SENP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-SENP1 Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-SENP1 Antibody, Affinity Purified

Predicted Reactivity: Orangutan

Purification: Affinity Purified

Immunogen: between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SENP1

Target: SENP1 (SUMO1/sentrin Specific Peptidase 1 (SENP1))

Alternative Name: SENP1

Background: Background: SENP1 (sentrin-specific protease) functions as a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugation of SUMO1 from HDAC1 decreases its transcriptional repression activity. SENP1 also deconjugates SUMO1 from HIPK2 [taken from the Universal Protein Resource (UniProt) Q9P0U3].

Gene ID: 29843

NCBI Accession: NP_055369

UniProt: Q9P0U3

Pathways: Positive Regulation of Endopeptidase Activity