SIPA1 antibody (AA 992-1042)

Catalog No. ABIN7452043

This Rabbit Polyclonal antibody specifically detects SIPA1 in WB and IP. It exhibits reactivity toward Human and Mouse.

Quick Overview for SIPA1 antibody (AA 992-1042) (ABIN7452043)

Target: SIPA1 (Signal-Induced Proliferation-Associated 1 (SIPA1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIPA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-SIPA1 Antibody

Binding Specificity: AA 992-1042

Purpose: Rabbit anti-SIPA1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 992 and 1042

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SIPA1

Target: SIPA1 (Signal-Induced Proliferation-Associated 1 (SIPA1))

Alternative Name: SIPA1

Background: Background: The regulation of GTPase activity is achieved via activators called GEFs (guanine-nucleotide exchange factors) and inactivators called GAPs (GTPase-activating proteins). Signal-induced proliferation-associated protein 1 (SIPA1) is a GTPase activating protein (GAP) for the Rap1 and Rap2 small GTPases. Spa-1 has been found to play an important role in hematopoietic cell development and the invasion and metastasis of human cancers.

Gene ID: 6494

NCBI Accession: NP_006738

UniProt: Q96FS4

Pathways: Response to Water Deprivation