SRGAP1 antibody (AA 979-1029)

Catalog No. ABIN7452067

This Rabbit Polyclonal antibody specifically detects SRGAP1 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for SRGAP1 antibody (AA 979-1029) (ABIN7452067)

Target: SRGAP1 (SLIT-ROBO rho GTPase Activating Protein 1 (SRGAP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRGAP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-SRGAP1 Antibody

Binding Specificity: AA 979-1029

Purpose: Rabbit anti-SRGAP1/ARHGAP13 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 979 and 1029

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SRGAP1

Target: SRGAP1 (SLIT-ROBO rho GTPase Activating Protein 1 (SRGAP1))

Alternative Name: SRGAP1/ARHGAP13

Background: Background: SRGAP1/ARHGAP13 is a member of the srGAP family of proteins that contain a RhoGAP domain, an SH3 domain, and a Fes/CIP4 homology domain and interact with the intracellular domain of roundabout 1 (Robo1). Robo1 is the receptor for Slit signaling and is involved in neuronal cell migration and axon tract positioning. SRGAP1/ARHGAP13 functions to bind and decrease the level of active Cdc42 and RhoA small GTPases during Slit-Robo signaling.

Gene ID: 57522

NCBI Accession: NP_065813

UniProt: Q7Z6B7