RRN3 antibody (AA 601-651)

Catalog No. ABIN7452098

The Rabbit Polyclonal anti-RRN3 antibody is suitable to detect RRN3 in samples from Human. It has been validated for WB and IP.

Quick Overview for RRN3 antibody (AA 601-651) (ABIN7452098)

Target: RRN3 (RRN3 RNA Polymerase I Transcription Factor (RRN3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RRN3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-RRN3 Antibody

Binding Specificity: AA 601-651

Purpose: Rabbit anti-TIF-IA Antibody, Affinity Purified

Predicted Reactivity: Orangutan

Purification: Affinity Purified

Immunogen: between AA 601 and 651

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for RRN3

Target: RRN3 (RRN3 RNA Polymerase I Transcription Factor (RRN3))

Alternative Name: TIF-IA

Background: Background: Transcription initiation factor IA (TIF-IA) is encoded by the RRN3 gene which was identified and cloned due to its homology with the yeast Rrn3p gene. TIF-IA has been shown to recruit initiation-competent RNA Polymerase I to rRNA promoters.

Gene ID: 54700

NCBI Accession: NP_060897

UniProt: Q9NYV6

Pathways: Negative Regulation of intrinsic apoptotic Signaling