TRIM25 antibody (AA 75-125)

Catalog No. ABIN7452117

This anti-TRIM25 antibody is a Rabbit Polyclonal antibody detecting TRIM25 in WB and IP. Suitable for Human.

Quick Overview for TRIM25 antibody (AA 75-125) (ABIN7452117)

Target: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM25 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-TRIM25 Antibody

Binding Specificity: AA 75-125

Purpose: Rabbit anti-TRIM25 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 75 and 125

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for TRIM25

Target: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Alternative Name: TRIM25

Background: Background: TRIM (tripartite motif) proteins, also known as RBCC (RING, B-box, coiled-coil) proteins, are defined by the presence of a tripartite structural motif composed of a RING domain, one or two B-box motifs, and a coiled-coil region. TRIM proteins have been found to be involved in a variety of cellular processes such as apoptosis, proliferation, differentiation, and innate immunity. Of these processes, the most intriguing is their involvement in the innate immune response. TRIM25 has been demonstrated to mediate ubiquitination of the cytosolic receptor retinoic acid-inducible gene-I (RIG-I) in response to viral infection.

Gene ID: 7706

NCBI Accession: NP_005073

UniProt: Q14258