UVRAG antibody (AA 575-625)

Catalog No. ABIN7452148

This Rabbit Polyclonal antibody specifically detects UVRAG in WB and IP. It exhibits reactivity toward Human.

Quick Overview for UVRAG antibody (AA 575-625) (ABIN7452148)

Target: UVRAG (UV Radiation Resistance Associated Gene (UVRAG))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UVRAG antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-UVRAG Antibody

Binding Specificity: AA 575-625

Purpose: Rabbit anti-UVRAG Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 575 and 625

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for UVRAG

Target: UVRAG (UV Radiation Resistance Associated Gene (UVRAG))

Alternative Name: UVRAG

Background: Background: UV radiation resistance associated gene (UVRAG) was first identified as a gene that could complement UV sensitivity in xeroderma pigmentosum cells. UVRAG may have tumor suppressor activity as mutations in the UVRAG gene have been associated with various human colon cancer cells and tissues. UVRAG has been shown to interact with Beclin 1 (Bcl-2-interacting protein), a protein that forms a complex with class III PI-3-kinase (PI3KC3) and is involved in autophagy. In this complex, UVRAG is proposed to function as a positive regulator of autophagy and a negative regulator of the growth of tumor cells.

Gene ID: 7405

NCBI Accession: NP_003360

UniProt: Q9P2Y5