WWP1 antibody (AA 200-250)

Catalog No. ABIN7452169

This Rabbit Polyclonal antibody specifically detects WWP1 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for WWP1 antibody (AA 200-250) (ABIN7452169)

Target: WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WWP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-WWP1 Antibody

Binding Specificity: AA 200-250

Purpose: Rabbit anti-WWP1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 200 and 250

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for WWP1

Target: WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))

Alternative Name: WWP1

Background: Background: WW domain-containing protein 1 (WWP1) functions as an E3 ubiquitin-protein ligase. WWP1 ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation. WWP1 also ubiquitinates and promotes degradation of TGFBR1, TGFBR1 ubiquitination is enhanced by SMAD7, and WWP1 also ubiquitinates SMAD7 as well as SMAD6. [taken from the Universal Protein Resource (UniProt) Q9H0M0].

Gene ID: 11059

NCBI Accession: NP_008944

UniProt: Q9H0M0