STK3 antibody (AA 400-450)

Catalog No. ABIN7452214

This Rabbit Polyclonal antibody specifically detects STK3 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for STK3 antibody (AA 400-450) (ABIN7452214)

Target: STK3 (serine/threonine Kinase 3 (STK3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STK3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-STK3 Antibody

Binding Specificity: AA 400-450

Purpose: Rabbit anti-MST2/STK3 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 400 and 450

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:500 - 1:2,500

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for STK3

Target: STK3 (serine/threonine Kinase 3 (STK3))

Alternative Name: MST2/STK3

Background: Background: MST2/STK3 is a member of the sterile 20 (Ste20)-like kinase family that acts upstream of mitogen-activated protein kinase (MAPK) pathways and regulates c-Jun N-terminal kinase (JNK), p38 and extracellular signal-regulated kinase (ERK). Ste20-like kinases are involved in a variety of cellular processes which include gene transcription, stress responses, cytoskeletal organization and apoptosis. In response to apoptotic signals, MST2/STK3 is cleaved by caspase-3 and mediates apoptosis.

Gene ID: 6788

NCBI Accession: NP_006272

UniProt: Q13188

Pathways: Tube Formation