Coiled-Coil Domain Containing 88C (CCDC88C) (AA 1450-1500) antibody

Catalog No. ABIN7452244

This Rabbit Polyclonal antibody specifically detects in IP. It exhibits reactivity toward Human.

Quick Overview for Coiled-Coil Domain Containing 88C (CCDC88C) (AA 1450-1500) antibody (ABIN7452244)

Target: Coiled-Coil Domain Containing 88C (CCDC88C)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Immunoprecipitation (IP)

Product Details

Binding Specificity: AA 1450-1500

Purpose: Rabbit anti-Daple Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1450 and 1500

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. ABIN7452244 has not performed satisfactorily when used for WB of Daple in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of Daple.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details

Target: Coiled-Coil Domain Containing 88C (CCDC88C)

Alternative Name: Daple

Background: Background: Daple (Dvl-associating protein with a high frequency of leucine residues) is a negative regulator of the canonical Wnt signaling pathway and acts downstream of DVL to inhibit CTNNB1/Beta-catenin stabilization [taken from the Universal Protein Resource (UniProt) Q9P219].

Gene ID: 440193

NCBI Accession: NP_001073883

UniProt: Q9P219