FZD6 antibody (AA 656-706)

Catalog No. ABIN7452245

The Rabbit Polyclonal anti-FZD6 antibody has been validated for IP. It is suitable to detect FZD6 in samples from Human.

Quick Overview for FZD6 antibody (AA 656-706) (ABIN7452245)

Target: FZD6 (Frizzled Family Receptor 6 (FZD6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FZD6 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-FZD6 Antibody

Binding Specificity: AA 656-706

Purpose: Rabbit anti-Frizzled-6 Antibody, Affinity Purified

Predicted Reactivity: Orangutan

Purification: Affinity Purified

Immunogen: between AA 656 and 706

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. ABIN7452245 has not performed satisfactorily when used for WB of Frizzled-6 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of Frizzled-6.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for FZD6

Target: FZD6 (Frizzled Family Receptor 6 (FZD6))

Alternative Name: Frizzled-6

Background: Background: Frizzled-6 is a receptor for Wnt proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin, and activation of wnt target genes. In mice, frizzled-6 is critical to B-cell development.

Gene ID: 8323

NCBI Accession: NP_003497

UniProt: O60353

Pathways: WNT Signaling, Tube Formation