FGFR1OP antibody (AA 349-399)
Quick Overview for FGFR1OP antibody (AA 349-399) (ABIN7452331)
Target
See all FGFR1OP AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 349-399
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Purpose
- Rabbit anti-FOP Antibody, Affinity Purified
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Predicted Reactivity
- Mouse,Rat,Bovine
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Purification
- Affinity Purified
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Immunogen
- between AA 349 and 399
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Isotype
- IgG
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Application Notes
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-FOP antibody ABIN7451589.
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- FGFR1OP (FGFR1 Oncogene Partner (FGFR1OP))
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Alternative Name
- FOP
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Background
- Background: FOP (FGFR1 Oncogene Partner) was identified and cloned as part of a translocation breakpoint in which the protein kinase domain of the FGFR1 (Fibroblast Growth Factor Receptor 1) gene is fused to the leucine-rich domain of FOP. Translocations involving FOP and FGFR1 are associated with stem cell myeloproliferative disorder (MPD). FOP has also been identified as a part of a centrosomal complex and has been shown to be required for the anchoring and organization of the microtubule network to subcellular structures.
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Gene ID
- 11116
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NCBI Accession
- NP_008976
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UniProt
- O95684
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Pathways
- M Phase, Maintenance of Protein Location, SARS-CoV-2 Protein Interactome
Target
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