OPTN antibody (AA 1-50)
Quick Overview for OPTN antibody (AA 1-50) (ABIN7452381)
Target
See all OPTN AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
 - AA 1-50
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Purpose
 - Rabbit anti-Optineurin Antibody, Affinity Purified
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Predicted Reactivity
 - Orangutan,Monkey
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Purification
 - Affinity Purified
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Immunogen
 - between AA 1 and 50
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Isotype
 - IgG
 
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Application Notes
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-Optineurin antibody ABIN7451913.
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Restrictions
 - For Research Use only
 
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Concentration
 - 1000 μg/mL
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Buffer
 - Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Preservative
 - Sodium azide
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Precaution of Use
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
 - 4 °C
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Expiry Date
 - 12 months
 
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- OPTN (Optineurin (OPTN))
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Alternative Name
 - Optineurin
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Background
 - Background: Defects in optineurin have been linked to glaucoma. In the cell, optineurin localizes to the Golgi and associates with markers of the endocytic pathway. A role in membrane trafficking and golgi function has been proposed due to its association with the actin-based motor protein myosin VI and its function as an effector protein of the small GTPase Rab8.
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Gene ID
 - 10133
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NCBI Accession
 - NP_068815
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UniProt
 - Q96CV9
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Pathways
 - M Phase
 
Target
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