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OPTN antibody (AA 1-50)

This anti-OPTN antibody is a Rabbit Polyclonal antibody detecting OPTN in IP. Suitable for Human.
Catalog No. ABIN7452381

Quick Overview for OPTN antibody (AA 1-50) (ABIN7452381)

Target

See all OPTN Antibodies
OPTN (Optineurin (OPTN))

Reactivity

  • 54
  • 34
  • 16
  • 7
  • 6
  • 5
  • 5
  • 5
  • 2
  • 2
  • 1
Human

Host

  • 54
  • 5
Rabbit

Clonality

  • 53
  • 6
Polyclonal

Conjugate

  • 33
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This OPTN antibody is un-conjugated

Application

  • 51
  • 14
  • 13
  • 13
  • 13
  • 11
  • 8
  • 7
  • 5
  • 3
  • 2
Immunoprecipitation (IP)
  • Binding Specificity

    • 15
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-50

    Purpose

    Rabbit anti-Optineurin Antibody, Affinity Purified

    Predicted Reactivity

    Orangutan,Monkey

    Purification

    Affinity Purified

    Immunogen

    between AA 1 and 50

    Isotype

    IgG
  • Application Notes

    IP: 2 - 5 μg/mg lysate

    WB: Not recommended. Use rabbit anti-Optineurin antibody ABIN7451913.

    Restrictions

    For Research Use only
  • Concentration

    1000 μg/mL

    Buffer

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C

    Expiry Date

    12 months
  • Target

    OPTN (Optineurin (OPTN))

    Alternative Name

    Optineurin

    Background

    Background: Defects in optineurin have been linked to glaucoma. In the cell, optineurin localizes to the Golgi and associates with markers of the endocytic pathway. A role in membrane trafficking and golgi function has been proposed due to its association with the actin-based motor protein myosin VI and its function as an effector protein of the small GTPase Rab8.

    Gene ID

    10133

    NCBI Accession

    NP_068815

    UniProt

    Q96CV9

    Pathways

    M Phase
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