F2RL3 antibody (AA 290-340)
Quick Overview for F2RL3 antibody (AA 290-340) (ABIN7452389)
Target
See all F2RL3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 290-340
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Purpose
- Rabbit anti-Par4 Antibody, Affinity Purified
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Predicted Reactivity
- Mouse,Rat
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Purification
- Affinity Purified
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Immunogen
- between AA 290 and 340
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Isotype
- IgG
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Application Notes
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-Par4 antibody ABIN7451935.
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- F2RL3 (Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3))
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Alternative Name
- Par4
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Background
- Background: Par4 (prostate apoptosis response-4) was identified in a differential screen for pro-apoptotic genes in a prostate carcinoma cell line. Par4 activates apoptosis via the Fas prodeath pathway and by inhibition of NF-kappa-B transcriptional activity. Par4 may be a tumor suppressor. It has been shown to interact with a wide variety of proteins including atypical PKCs, and the Wilms' tumor suppressor.
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Gene ID
- 5074
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NCBI Accession
- NP_002574
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UniProt
- Q96IZ0
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Pathways
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
Target
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