PPP6R3 antibody (AA 400-450)

Catalog No. ABIN7452425

The Rabbit Polyclonal anti-PPP6R3 antibody has been validated for IP. It is suitable to detect PPP6R3 in samples from Human.

Quick Overview for PPP6R3 antibody (AA 400-450) (ABIN7452425)

Target: PPP6R3 (Protein Phosphatase 6, Regulatory Subunit 3 (PPP6R3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP6R3 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-PPP6R3 Antibody

Binding Specificity: AA 400-450

Purpose: Rabbit anti-SAPS3 Antibody, Affinity Purified

Predicted Reactivity: Mouse

Purification: Affinity Purified

Immunogen: between AA 400 and 450

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-SAPS3 antibody ABIN7452028.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PPP6R3

Target: PPP6R3 (Protein Phosphatase 6, Regulatory Subunit 3 (PPP6R3))

Alternative Name: SAPS3

Background: Background: SAPS3 is a regulatory subunit of the PP6 phosphatase. There are 3 human SAPs (sit4-associated proteins), SAPS1, SAPS2, and SAPS3. The human SAPs are related to SAPs found in yeast that associate with the sit4 phosphatase which is the homolog of human PP6 phosphatase. In yeast sit4 and its associated SAPs are involved in a variety of processes which include transcription, translation, bud formation, glycogen metabolism, ion homeostasis, and telomere function. Because the SAPS3 gene maps to the IDDM4 locus at 11q13, SAPS3 has been implicated in insulin-dependent diabetes mellitus. SAPS domain family member 3, protein phosphatase 6 regulatory subunit 3, PP6R3, and KIAA1558.

Gene ID: 55291

NCBI Accession: NP_060782

UniProt: Q5H9R7