GAN antibody (AA 50-100)

Catalog No. ABIN7452509

The Rabbit Polyclonal anti-GAN antibody has been validated for IP. It is suitable to detect GAN in samples from Human.

Quick Overview for GAN antibody (AA 50-100) (ABIN7452509)

Target: GAN (Gigaxonin (GAN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAN antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-GAN Antibody

Binding Specificity: AA 50-100

Purpose: Rabbit anti-Gigaxonin Antibody, Affinity Purified

Predicted Reactivity: Mouse

Purification: Affinity Purified

Immunogen: between AA 50 and 100

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: Not recommended

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for GAN

Target: GAN (Gigaxonin (GAN))

Alternative Name: Gigaxonin

Background: Background: Gigaxonin is a probable cytoskeletal component that directly or indirectly plays an important role in neurofilament architecture. It is also a substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins such as TBCB, MAP1B, and MAP1S and is critical for neuronal maintenance and survival [taken from the Universal Protein Resource (UniProt) Q9H2C0].

Gene ID: 8139

NCBI Accession: NP_071324

UniProt: Q9H2C0