Recombinant CDK1 antibody (pTyr15)

Catalog No. ABIN7452577

This Rabbit Monoclonal antibody specifically detects CDK1 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for Recombinant CDK1 antibody (pTyr15) (ABIN7452577)

Target: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CDK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: BLR101H

Product Details anti-CDK1 Antibody

Binding Specificity: pTyr15

Purpose: Rabbit anti-Phospho CDK1 (Y15) Recombinant Monoclonal Antibody [BLR101H]

Immunogen: surrounding tyrosine 15

Isotype: IgG

Application Details

Application Notes:

IP: 20 μL/1 mg lysate

WB: 01:01,00

Restrictions: For Research Use only

Handling

Concentration: 40 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CDK1

Target: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Alternative Name: CDK1

Background: Background: Cyclin-dependent kinase 1 (CDK1) is a member of the Ser/Thr protein kinase family. CDK1 is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of CKD1 is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control [taken from NCBI Entrez Gene (Gene ID: 983)].

Gene ID: 983

NCBI Accession: NP_001777

UniProt: P06493

Pathways: Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA