FNBP1 antibody (AA 567-617)

Catalog No. ABIN7452760

This Rabbit Polyclonal antibody specifically detects FNBP1 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for FNBP1 antibody (AA 567-617) (ABIN7452760)

Target: FNBP1 (Formin Binding Protein 1 (FNBP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FNBP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-FNBP1 Antibody

Binding Specificity: AA 567-617

Purpose: Rabbit anti-FBP17 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 567 and 617

Isotype: IgG

Application Details

Application Notes:

IP: 5 - 15 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for FNBP1

Target: FNBP1 (Formin Binding Protein 1 (FNBP1))

Alternative Name: FBP17

Background: Background: FBP17 may act as a link between RND2 signaling and regulation of the actin cytoskeleton. FBP17 is required for the coordination of membrane tubulation and reorganization of the actin cytoskeleton during endocytosis. FBP17 binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. It also enhances actin polymerization via the recruitment of WASL/N-WASP, which in turn activates the Arp2/3 complex. FBP17 may be required for the lysosomal retention of FASLG/FASL [taken from the Universal Protein Resource (UniProt) Q96RU3].

Gene ID: 23048

NCBI Accession: NP_055848

UniProt: Q96RU3