CCDC94 antibody (AA 273-323)

Catalog No. ABIN7452810

This anti-CCDC94 antibody is a Rabbit Polyclonal antibody detecting CCDC94 in WB and IP. Suitable for Human.

Quick Overview for CCDC94 antibody (AA 273-323) (ABIN7452810)

Target: CCDC94 (Coiled-Coil Domain Containing 94 (CCDC94))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC94 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-CCDC94 Antibody

Binding Specificity: AA 273-323

Purpose: Rabbit anti-CCDC94 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 273 and 323

Isotype: IgG

Application Details

Application Notes:

IP: 50-100 μL/mg lysate

WB: 1:10,000 - 1:25,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CCDC94

Target: CCDC94 (Coiled-Coil Domain Containing 94 (CCDC94))

Alternative Name: CCDC94

Background: Background: CCDC94 is part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. CCDC94 also plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. CCDC94 may protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex. [taken from the Universal Protein Resource (UniProt) Q9BW85].

Gene ID: 55702

UniProt: Q9BW85