COPA antibody (AA 1174-1224)
Quick Overview for COPA antibody (AA 1174-1224) (ABIN7453067)
Target
See all COPA AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1174-1224
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Purpose
- Rabbit anti-COPA Antibody, Affinity Purified
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Predicted Reactivity
- Bovine
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Purification
- Affinity Purified
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Immunogen
- Between AA 1174 and 1224
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Isotype
- IgG
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Application Notes
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IP: Not recommended
WB: 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- COPA (Coatomer Protein Complex, Subunit alpha (COPA))
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Alternative Name
- COPA
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Background
- Background: In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone [taken from NCBI Entrez Gene (Gene ID: 1314)].
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Gene ID
- 1314
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NCBI Accession
- NP_004362
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UniProt
- P53621
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Pathways
- Hormone Activity
Target
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