Gephyrin antibody (AA 686-736)

Catalog No. ABIN7453092

This anti-Gephyrin antibody is a Rabbit Polyclonal antibody detecting Gephyrin in WB. Suitable for Human.

Quick Overview for Gephyrin antibody (AA 686-736) (ABIN7453092)

Target: Gephyrin (GPHN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Gephyrin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Gephyrin Antibody

Binding Specificity: AA 686-736

Purpose: Rabbit anti-Gephyrin Antibody, Affinity Purified

Predicted Reactivity: Mouse,Rat,Chicken

Purification: Affinity Purified

Immunogen: Between AA 686 and 736

Isotype: IgG

Application Details

Application Notes:

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Gephyrin

Target: Gephyrin (GPHN)

Alternative Name: Gephyrin

Background: Background: Gephyrin is a microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules (By similarity). Gephyrin catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is release [taken from the Universal Protein Resource (UniProt) Q9NQX3].

Gene ID: 10243

NCBI Accession: NP_001019389

UniProt: Q9NQX3

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development