IDH3B antibody (AA 25-75)

Catalog No. ABIN7453107

This anti-IDH3B antibody is a Rabbit Polyclonal antibody detecting IDH3B in WB. Suitable for Human and Mouse.

Quick Overview for IDH3B antibody (AA 25-75) (ABIN7453107)

Target: IDH3B (Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IDH3B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IDH3B Antibody

Binding Specificity: AA 25-75

Purpose: Rabbit anti-IDH3B Antibody, Affinity Purified

Predicted Reactivity: Pig,Orangutan

Purification: Affinity Purified

Immunogen: Between AA 25 and 75

Isotype: IgG

Application Details

Application Notes:

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for IDH3B

Target: IDH3B (Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B))

Alternative Name: IDH3B

Background: Background: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit.Isocitric dehydrogenase subunit beta (IDH3B) is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase [taken from NCBI Entrez Gene (Gene ID: 3420)].

Gene ID: 3420

UniProt: O43837