MID1 antibody (AA 617-667)
Quick Overview for MID1 antibody (AA 617-667) (ABIN7453135)
Target
See all MID1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 617-667
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Purpose
- Rabbit anti-MID1 Antibody, Affinity Purified
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Predicted Reactivity
- Rat
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Purification
- Affinity Purified
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Immunogen
- between AA 617 and 667
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Isotype
- IgG
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Application Notes
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IP: Not recommended
WB: 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- MID1 (Midline 1 (MID1))
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Alternative Name
- MID1
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Background
- Background: Defects in the Midline-1 (MID1) gene are the cause of Opitz syndrome, an X-linked recessive disorder characterized by developmental defects. MID1 is a microtubule-associated protein (MAP) with E3 ubiquitin ligase activity. MID1 has been shown to target protein phosphatases 2A (PP2Ac) on microtubules for degradation. MID1 association with PP2A has been proposed to regulate microtubule stabilization for cellular processes such as cell division and migration.
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Gene ID
- 4281
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NCBI Accession
- NP_000372
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UniProt
- O15344
Target
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