PTRH2 antibody (AA 129-179)

Catalog No. ABIN7453173

This anti-PTRH2 antibody is a Rabbit Polyclonal antibody detecting PTRH2 in WB. Suitable for Human.

Quick Overview for PTRH2 antibody (AA 129-179) (ABIN7453173)

Target: PTRH2 (Peptidyl-tRNA Hydrolase 2 (PTRH2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTRH2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PTRH2 Antibody

Binding Specificity: AA 129-179

Purpose: Rabbit anti-PTRH2/BIT1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 129 and 179

Isotype: IgG

Application Details

Application Notes:

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PTRH2

Target: PTRH2 (Peptidyl-tRNA Hydrolase 2 (PTRH2))

Alternative Name: PTRH2/BIT1

Background: Background: Peptidyl-tRNA hydrolase 2 (PTRH2) is a mitochondrial protein with two putative domains, an N-terminal mitochondrial localization sequence, and a UPF0099 domain. In vitro assays suggest that this protein possesses peptidyl-tRNA hydrolase activity, to release the peptidyl moiety from tRNA, thereby preventing the accumulation of dissociated peptidyl-tRNA that could reduce the efficiency of translation. This protein also plays a role regulating cell survival and death. It promotes survival as part of an integrin-signaling pathway for cells attached to the extracellular matrix (ECM), but also promotes apoptosis in cells that have lost their attachment to the ECM, a process called anoikos [taken from NCBI Entrez Gene (Gene ID: 51651)].

Gene ID: 51651

UniProt: Q9Y3E5