ARVCF antibody (AA 75-125)

Catalog No. ABIN7453257

The Rabbit Polyclonal anti-ARVCF antibody (ABIN7453257) specifically detects ARVCF in WB. The antibody is reactive with Human samples.

Quick Overview for ARVCF antibody (AA 75-125) (ABIN7453257)

Target: ARVCF (Armadillo Repeat Gene Deleted in Velocardiofacial Syndrome (ARVCF))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARVCF antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ARVCF Antibody

Binding Specificity: AA 75-125

Purpose: Rabbit anti-ARVCF Antibody, Affinity Purified

Predicted Reactivity: Mouse

Purification: Affinity Purified

Immunogen: between AA 75 and 125

Isotype: IgG

Application Details

Application Notes:

IP: Not recommended

WB: 1:500 - 1:2,500

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for ARVCF

Target: ARVCF (Armadillo Repeat Gene Deleted in Velocardiofacial Syndrome (ARVCF))

Alternative Name: ARVCF

Background: Background: Armadillo repeat gene deleted in velocardiofacial syndrome (ARVCF) is a member of the catenin family. This family plays an important role in the formation of adherens junction complexes, which are thought to facilitate communication between the inside and outside environments of a cell. The ARVCF gene was isolated in the search for the genetic defect responsible for the autosomal dominant Velo-Cardio-Facial syndrome (VCFS), a relatively common human disorder with phenotypic features including cleft palate, conotruncal heart defects and facial dysmorphology. The ARVCF gene encodes a protein containing two motifs, a coiled coil domain in the N-terminus and a 10 armadillo repeat sequence in the midregion. Since these sequences can facilitate protein-protein interactions ARVCF is thought to function in a protein complex. In addition, ARVCF contains a predicted nuclear-targeting sequence suggesting that it may have a function as a nuclear protein [taken from NCBI Entrez Gene (Gene ID: 421)].

Gene ID: 421

NCBI Accession: NP_001661

UniProt: O00192