STAG2 antibody (AA 1125-1175)

Catalog No. ABIN7453336

This Goat Polyclonal antibody specifically detects STAG2 in WB, ICC and IP. It exhibits reactivity toward Human and Mouse.

Quick Overview for STAG2 antibody (AA 1125-1175) (ABIN7453336)

Target: STAG2 (Stromal Antigen 2 (STAG2))

Reactivity: Human, Mouse

Host: Goat

Clonality: Polyclonal

Conjugate: This STAG2 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Product Details anti-STAG2 Antibody

Binding Specificity: AA 1125-1175

Purpose: Goat anti-SA2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1125 and 1175

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

ICC: 1:500 - 1:2,000

WB: 1:1,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for STAG2

Target: STAG2 (Stromal Antigen 2 (STAG2))

Alternative Name: STAG2

Background: Background: SA2 is a component of the multisubunit cohesin complex. Cohesin functions to hold sister chromatids together during meiosis and mitosis and ensure proper segregation of chromosomes. Cohesin must dissociate from sister chromatids during prophase and metaphase so that they can segregate to opposite poles of the cell during anaphase. As part of the cohesin complex, SA2 appears to play a role in cohesin dissociation required for sister chromatid separation. Interestingly, SA2 has been demonstrated to also exhibit transcriptional regulatory activity through an association with NF-kappaB.

Gene ID: 10735

NCBI Accession: NP_006594

UniProt: Q8N3U4

Pathways: Stem Cell Maintenance