Recombinant NOS2 antibody (AA 1094-1144)

Catalog No. ABIN7453345

This Rabbit Monoclonal antibody specifically detects NOS2 in WB, IP and ICC. It exhibits reactivity toward Mouse.

Quick Overview for Recombinant NOS2 antibody (AA 1094-1144) (ABIN7453345)

Target: NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))

Antibody Type: Recombinant Antibody

Reactivity: Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This NOS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: BLR181J

Product Details anti-NOS2 Antibody

Binding Specificity: AA 1094-1144

Purpose: Rabbit anti-iNOS Recombinant Monoclonal Antibody [BLR181J]

Purification: Purified

Immunogen: between AA 1094 and 1144 (C-term)

Isotype: IgG

Application Details

Application Notes:

IP: 6 μL/1 mg lysate

ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

WB: 17:40:00

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2 - 8 °C

Expiry Date: 12 months

Target Details for NOS2

Target: NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))

Alternative Name: iNOS

Background: Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide synthase is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. [taken from NCBI Entrez Gene (Gene ID: 4843)].

Gene ID: 18126

UniProt: P29477

Pathways: Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Inositol Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process