BCR antibody (AA 50-100)

Catalog No. ABIN7453395

This anti-BCR antibody is a Rabbit Polyclonal antibody detecting BCR in WB, FACS, IP and IF/ICC. Suitable for Human.

Quick Overview for BCR antibody (AA 50-100) (ABIN7453395)

Target: BCR (Breakpoint Cluster Region (BCR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCR antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (fixed cells) (IF/ICC)

Product Details anti-BCR Antibody

Binding Specificity: AA 50-100

Purpose: Rabbit anti-BCR Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 50 and 100

Isotype: IgG

Application Details

Application Notes:

ICC-IF: 1:500 - 1:2,000

IP: 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-BCR antibody ABIN7453394.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for BCR

Target: BCR (Breakpoint Cluster Region (BCR))

Alternative Name: BCR

Background: Background: BCR (breakpoint cluster region) was identified as part of a fusion protein that results from a reciprocal translocation with the ABL gene between chromosomes 22 and 9. The BCR-ABL fusion is the cause of chronic myeloid leukemia (CML). The BCR protein contains a C2 domain, a DBL-homology domain, a PH domain, and a Rho-GAP domain and functions as a GTPase-activating protein for RAC1 and CDC42.

Gene ID: 613

NCBI Accession: NP_004318

UniProt: P11274

Pathways: Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling