DLD antibody (AA 459-509)

Catalog No. ABIN7453411

This Rabbit Polyclonal antibody specifically detects DLD in WB, IP and IHC (fp). It exhibits reactivity toward Human and Mouse.

Quick Overview for DLD antibody (AA 459-509) (ABIN7453411)

Target: DLD (Dihydrolipoamide Dehydrogenase (DLD))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLD antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-DLD Antibody

Binding Specificity: AA 459-509

Purpose: Rabbit anti-DLD Antibody, Affinity Purified

Predicted Reactivity: Dog,Orangutan

Purification: Affinity Purified

Immunogen: Between AA 459 and 509

Isotype: IgG

Application Details

Application Notes:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for DLD

Target: DLD (Dihydrolipoamide Dehydrogenase (DLD))

Alternative Name: DLD

Background: Background: Dihydrolipoamide dehydrogenase (DLD) is a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. DLD has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, DLD functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism. However, as a monomer, this protein can function as a protease. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency [taken from NCBI Entrez Gene (Gene ID: 1738)].

Gene ID: 1738

NCBI Accession: NP_000099

UniProt: P09622

Pathways: Ribonucleoside Biosynthetic Process, Cell RedoxHomeostasis